Twitter Digest for November 3, 2017

Twitter Digest for November 2, 2017

Spotlight on Cerebral venous thrombosis in infants and children

In this article, Dr. Mahendranath Moharir and Dr. Gabrielle deVeber of the University of Toronto discuss cerebral sinovenous thrombosis. The condition is often unrecognized in neonates and children due to nonspecific clinical features and challenges in radiographic diagnosis. Risk factors for cerebral sinovenous thrombosis in neonates are different from those in older children. Treatment with anticoagulants, a well-established practice in adults, is increasingly offered in children and, to a lesser extent, in neonates. The safety of anticoagulants and recanalization outcomes in cerebral sinovenous thrombosis has been established in children as well as in neonates based on consecutive cohort studies; however, its influence on neurologic outcome, particularly in neonates, has not been proven. The clinical outcome from cerebral sinovenous thrombosis remains worse in neonates than in children.

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Twitter Digest for November 1, 2017

Twitter Digest for October 31, 2017

Twitter Digest for October 30, 2017

Twitter Digest for October 27, 2017

Twitter Digest for October 26, 2017

Spotlight on Neuroacanthocytosis

In this article, Dr. William Stamey of Mid Coast Hospital in Brunswick, Maine, discusses neuroacanthocytosis, a neurologic syndrome characterized by a broad spectrum of movement disorders that often share acanthocytes on the blood smear. In addition to a variety of hyperkinetic and hypokinetic movement disorders, behavioral and cognitive disturbances are common features. An autosomal recessive disorder, chorea-acanthocytosis overlaps clinically with McLeod syndrome, which is inherited as an X-linked disorder. Neuroacanthocytosis must be considered in the differential diagnosis of patients presenting with movement disorders and behavioral or cognitive findings. Treatments, including deep brain stimulation, are met with various levels of success.

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Twitter Digest for October 25, 2017