Hyperkinetic seizures are characterized by motor seizures involving predominantly proximal limb or axial muscles in irregular sequential ballistic movements. The origin of hyperkinetic seizures is more commonly localized in the mesial frontal or orbitofrontal regions. Seizures often occur during sleep and recur repeatedly, with intervals of a few seconds. Exclusively nocturnal hyperkinetic seizures are the typical spells in autosomal dominant nocturnal frontal lobe epilepsy. In this clinical summary, Drs. Ana Carolina Coan and Fernando Cendes of the Department of Neurology at University of Campinas – UNICAMP in Brazil present recent data and discussion about the causes, syndromes, diagnosis, and management of hypermotor seizures.
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