Spotlight on Multiple sclerosis: biological differences in children and adults

In this article, Dr. Susan Kim of the Sacramento VA Medical Center and Dr. Mark Agius of Barrow Neurological Institute discuss the particular concerns for children as compared to adults with multiple sclerosis.

The behavior of the immune system in children with multiple sclerosis appears to parallel that in children with other chronic inflammatory diseases. Children with multiple sclerosis represent a group in whom a strategy of induction of remission and maintenance of remission is likely to prevent long-term disability. The developing nervous system is a particularly susceptible target of the immune system. At the same time, the potential for enhanced neural plasticity in children provides a unique opportunity for functional recovery along with long-term disability prevention.

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