Blepharospasm is a form of focal dystonia manifested by involuntary eye closure due to excessive contractions of the eyelids. In addition, contractions of orbicularis oculi (pretarsal, preseptal, and periorbital portions) adjacent muscles, including procerus and corrugator, as well as paranasal and other facial muscles may be involved. Blepharospasm is often misdiagnosed as “dry eyes” or “nervousness.”
In this article, Dr. Joseph Jankovic of Baylor College of Medicine reviews the clinical features, pathogenesis, and treatment of blepharospasm, focusing on the use of botulinum toxin.
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