Spotlight on Cerebrovascular complications of cancer

Cerebrovascular disease (sinus thrombosis, cerebral infarction, or hemorrhage) is a common complication of cancer and of cancer therapy. In this article, Dr. Fernando Testai and Dr. Vinny Sharma of the University of Illinois College of Medicine at Chicago review the clinical milieu in which these disorders develop and summarize the methods of diagnosis, including characteristic abnormalities of clinical findings, coagulation function tests, and neuroimaging. The management of these vascular disorders can be challenging in this patient population because of comorbidities associated with cancer. Some vascular disorders are unique to the cancer patient, including radiation-induced carotid artery atherosclerosis and chemotherapy-induced vasculopathy. Until recently, reports of these latter conditions were anecdotal and infrequent.

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Spotlight on Hypercoagulable states and cerebrovascular disease

In this article,Dr. Kathryn Kirchoff-Torres of Albert Einstein College of Medicine discusses advances in understanding the epidemiology, pathophysiology, and management of patients with ischemic stroke and cerebral venous thrombosis associated with genetic and acquired thrombophilia. This article also provides an overview of recently published treatment guidelines for patients with cerebrovascular events and thrombophilias, including the antiphospholipid antibody syndrome.

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MedLink Neurology authors are always at work to bring you broad and up-to-date coverage of neurology topics. We are pleased to highlight clinical summaries that have been recently added or updated and to introduce the authors who write these authoritative articles. We hope you enjoy these overviews and appreciate the contributions of our more than 450 authors who keep MedLink Neurology the premier information resource for neurologists.

Spotlight on Headache associated with ischemic cerebrovascular disease

Headache often accompanies acute ischemic stroke. Observational studies indicate that 15% to 40% of patients with acute ischemic stroke report headache in close temporal relation to the event. The onset headache is more often seen in posterior circulation strokes than in strokes in other vascular territories. The pathophysiology of headache associated with acute ischemic stroke includes edema, hemorrhagic transformation, and changes in the trigeminovascular system. In this clinical summary, Dr. Hans-Christoph Diener of the University of Essen discusses headache associated with ichemic cerebrovascular disease.

To view the complete clinical summary, click here.

MedLink Neurology authors are always at work to bring you broad and up-to-date coverage of neurology topics. We are pleased to highlight clinical summaries that have been recently added or updated and to introduce the authors who write these authoritative articles. We hope you enjoy these overviews and appreciate the contributions of our more than 450 authors who keep MedLink Neurology the premier information resource for neurologists.